Title : Influence of contralateral knee status on Quality of Life (QoL) after Total Knee Replacement (TKR): Retrospective study
Abstract:
This retrospective cohort study evaluated the influence of contralateral knee status—native versus previously replaced—on postoperative quality of life (QoL) using the EQ-5D 3L index, in patients undergoing total knee replacement (TKR). Data from 100 patients (50 with a native contralateral knee and 50 with prior contralateral TKR) were analysed, comparing baseline and 6-month postoperative QoL.
The study demonstrated mean EQ-5D index improvements of 0.24 in patients with native contralateral knees and 0.32 in patients with prior contralateral TKR. Clinically meaningful QoL improvements (≥0.1 EQ-5D index) were seen in 47% of native contralateral knee patients compared to 78% in patients with prior contralateral TKR. Although greater improvement was observed in the prior TKR group, this difference was not statistically significant (p = 0.30).
Possible reasons for these findings include: 1) prior contralateral TKR providing better baseline stability and support, enhancing rehabilitation outcomes; 2) native contralateral knees potentially contributing to residual functional limitations, thereby limiting QoL improvements; and 3) diminishing incremental gains after second knee replacements.
These results underscore the clinical relevance of contralateral knee status when planning surgical interventions and rehabilitation strategies. Clearly communicating these potential outcomes can help manage patient expectations, improve satisfaction, and optimize postoperative recovery.
