Synergy of hyaluronic acid scaffold and BMAC in one-step chondral repair

Title : Synergy of hyaluronic acid scaffold and BMAC in one-step chondral repair

Abstract:

Articular cartilage defects remain a major challenge in orthopedic practice because of their limited intrinsic healing capacity. This presentation evaluates a one-step technique for knee chondral repair using a hyaluronic acid scaffold impregnated with Bone Marrow Aspirate Concentrate (BMAC). The biological rationale is based on the scaffold’s biocompatibility and the chondrogenic potential of mesenchymal stem cells contained in BMAC, with the aim of promoting hyaline-like tissue regeneration.

The procedure is performed in a single surgical stage after lesion debridement. Bone marrow is harvested intraoperatively, concentrated, and then applied to a Hyaff-11/Hyalofast scaffold before implantation into the defect. In selected patients with focal cartilage lesions, this approach has shown meaningful improvements in clinical outcomes, including pain reduction, functional recovery, and return to sport. MRI evaluation has also demonstrated progressive defect coverage and tissue repair.

This technique offers a reproducible and minimally invasive biological solution for cartilage restoration, particularly in carefully selected patients with focal ICRS grade III-IV lesions. Compared with traditional microfracture procedures, the combination of scaffold and BMAC may provide more durable repair tissue and better mid-term clinical results. Appropriate patient selection and structured rehabilitation remain essential for success.

Biography:

Massimo Piracci completed his MBBS from Roma Tor Vergata, Italy in 1992 and subsequently received his MD in Orthopedic and Traumatology from the same University in 1999. He was trained in Orthopedic Surgery in Roma Saint Eugenio Hospital and in Latina Santa Maria Goretti Hospital. From 2003 was HOD in Orthopedic and Traumatology Department in Roma Clinic Annunziatella where he did more than 10.000 surgery. He was also Football Referee for FIGC for 15 years and also external orthopedic consultant for different football team. From 2014 in UAE. He uses the most advanced technologies and biological implant (PRP, Stamina cells, Ozone Therapy) and mini invasive surgery of hip head. He treats the most of orthopedic pathology for children and adults, the most of minor and major trauma, and sport injury with advanced mini invasive technique. For low back pain he uses the treatment with Ozone therapy that resolve the pain giving back a normal life to the patient. He was the HOD of Orthopedic department in Czech Rehabilitation Hospital in Al Ain and HOD of Regenerative and Sport Medicine in Adam Vital Hospital in Dubai. Consultant Orthopedic Surgeon in Saudi German Hospital in Dubai. Consultant Orthopedic surgeon in Emirates Hospital Group, he is Consultant Orthopedic surgeon, Regenerative Medicine and Sport Medicine in Medcare Orthopedic Spinal Hospital Dubai. Speaker well known in many National and International Conference and publishing.