Title : A prospective study on the effect of different bone cement volumes in preventing vertebral collapse
Abstract:
Objective: To explore the impact of varying volumes of bone cement injected during percutaneous vertebroplasty (PVP) on preventing vertebral collapse following osteoporotic vertebral compression fractures (OVCF).
Methods: A prospective study included 90 OVCF patients treated at our hospital from January 2020 to December 2022. Patients were randomly divided into three groups of 30 each according to a random number table method: Group A received less than 4ml of bone cement, Group B received 4-6ml, and Group C more than 6ml. The visual analog scale (VAS), anterior vertebral height (AVH), posterior vertebral height (PVH), and segmental kyphotic angle (SKA) were recorded preoperatively, postoperatively, at six months and 12 months postoperatively. All patients were followed up at least 12 months.
Results: There were no significant differences among the three groups regarding gender, age, body mass index (BMI), disease duration, surgical segment, AVH, PVH, and VAS (P>0.05). Comparisons of AVH, PVH, SKA, and VAS postoperatively and six months postoperatively also showed no significant statistical differences among the three groups (P>0.05). At 12 months postoperatively, there were no significant differences in VAS among the three groups (P>0.05). However, Group B's AVH was significantly higher (17.5±2.6mm) compared to Group A (16.6±2.2mm) and Group C (16.8±2.1mm) (P<0.05). Group B's PVH was also significantly higher (19.7±2.4mm) compared to Group A (18.3±2.2mm) and Group C (18.6±2.1mm) (P<0.05). Additionally, Group B's SKA (8.8±1.5°) was significantly smaller than that of Group A (9.9±1.9°) and Group C (9.7±1.7°) (P<0.05).
Conclusion: For patients with OVCF, injecting 4-6 ml of bone cement into the vertebrae during PVP significantly prevents postoperative vertebral collapse.
Keywords: Percutaneous vertebroplasty, osteoporotic vertebral compression fractures, Bone Cement Volumes.
