The integration of biomechanics and 3D printing has revolutionized orthopedic treatments, offering personalized solutions for complex musculoskeletal conditions. Advances in biomechanics and 3D printing in orthopedics have enabled the creation of patient-specific implants, prosthetics, and surgical guides with unmatched precision. Biomechanical analysis helps in understanding joint mechanics, injury mechanisms, and rehabilitation strategies, leading to improved surgical planning and post-operative outcomes. 3D printing technology has further transformed orthopedic care by allowing for the rapid production of customized bone grafts and scaffolds, enhancing tissue regeneration and implant integration. Additionally, the combination of computational modeling with additive manufacturing is paving the way for more durable and biocompatible orthopedic implants. As research continues, these innovations are set to enhance treatment efficiency, reduce complications, and improve the quality of life for patients requiring orthopedic interventions.