Maintaining optimal musculoskeletal function requires a holistic approach that includes physical activity, dietary balance, and preventive care. Lifestyle and nutrition in musculoskeletal health play a crucial role in bone density, joint flexibility, and muscle strength, directly impacting the risk of conditions like osteoporosis, sarcopenia, and arthritis. A diet rich in calcium, vitamin D, and essential proteins supports bone metabolism and muscle repair, while anti-inflammatory foods help manage chronic musculoskeletal pain. Additionally, lifestyle factors such as regular weight-bearing exercise, proper posture, and stress management contribute to long-term orthopedic health. Emerging research highlights the impact of gut microbiota on musculoskeletal function, emphasizing the need for balanced nutrition in maintaining bone and joint integrity. By integrating dietary strategies with physical wellness, individuals can enhance mobility, reduce injury risk, and improve overall orthopedic outcomes, reinforcing the importance of preventive musculoskeletal care.