Neuromuscular disorders and orthopedic implications present complex challenges, as conditions affecting nerve and muscle function often lead to significant musculoskeletal complications. Disorders such as muscular dystrophy, cerebral palsy, and peripheral neuropathies can result in joint deformities, scoliosis, and impaired mobility, requiring specialized orthopedic interventions. Muscle weakness and spasticity contribute to abnormal gait patterns, joint contractures, and an increased risk of fractures due to reduced bone density. Advanced surgical techniques, including tendon transfers, osteotomies, and spinal stabilization procedures, are improving mobility and quality of life for affected individuals. Additionally, non-surgical approaches such as orthotic devices, neuromodulation, and targeted physical therapy play a crucial role in managing functional limitations. As research advances, the integration of gene therapy, stem cell treatments, and neurorehabilitation is opening new possibilities for treating both the neurological and orthopedic aspects of these conditions, offering more comprehensive care for individuals with neuromuscular disorders.