Orthopedic and Musculoskeletal Oncology

One of the more recent subspecialties in orthopaedics is orthopaedic oncology, or the art and science of managing musculoskeletal cancers. Amputation is no longer the only option for achieving local control in malignant bone tumours, due to remarkable advances in the field of musculoskeletal oncology during the previous few decades. In these lesions, function-preserving approaches have now become the standard, without compromising overall disease survival, and have resulted in a demonstrated improvement in patients' overall quality of life. The goals as surgeons have transformed, and the difficulty has shifted as well. It's no longer just about removing sickness and restoring function; it's also about doing it in the most cost-effective way possible.

Musculoskeletal oncology is a branch of orthopaedic surgery that focuses on the detection and treatment of benign and malignant cancers of the bone and connective tissues in children and adults. The diagnosis, therapy, and palliative care of patients with metastatic cancer to the skeleton are also included in this discipline. To treat patients with bone and soft tissue sarcomas, musculoskeletal oncologists collaborate with experts in musculoskeletal imaging, pathology, medical and paediatric oncology, radiation, and surgery.

• Adamantinoma
• Bone biomarkers (clinical and translational applications)
• Bone imaging (clinical and animal, skeletal interventional radiology)
• Bone metastases (pathophysiology, epidemiology, diagnostics, clinical features, prevention, treatment)
• Bone microenvironment in cancer (stem cell, bone cell and cancer interactions)
• Bone pain (mechanisms and management)
• Bone targeted therapy (pharmacology, therapeutic targets, drug development, clinical trials, side-effects, outcome research, health economics)
• Cancer treatment induced bone loss (epidemiology, pathophysiology, prevention and management)
• Chondrosarcoma
• Chordomas
• Clinical guidelines
• Malignant Osteoid
• Metastatic Bone Cancer
• Multidisciplinary care
• Multilobular Tumour of Bone
• Orthopaedic cancer surgery
• Osteosarcoma
• Preclinical models of metastasis
• Primary bone tumours
• Radiotherapy and radio-isotopes
• Skeletal complications