Metabolic Bone Diseases encompass a group of disorders affecting the structure and strength of bones, often due to abnormalities in mineral and hormone metabolism. Osteoporosis, a common metabolic bone disease, is characterized by reduced bone density and an increased risk of fractures. Paget's disease is another condition where bones become enlarged and deformed. Rickets, typically seen in childhood, results from a deficiency of vitamin D, calcium, or phosphate, leading to weakened and deformed bones. Hyperparathyroidism influences calcium regulation, causing bones to release excessive calcium into the bloodstream, leading to bone weakness. Osteogenesis imperfecta is a genetic disorder causing brittle bones and frequent fractures. These diseases disrupt the delicate balance of bone remodeling, impacting bone density and strength. Management often involves nutritional supplements, medications, and lifestyle modifications to support bone health.
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