Metastatic Bone Disease, also known as secondary Bone Cancer, occurs when cancer cells from a primary tumor elsewhere in the body spread (metastasize) to the bones. This condition is more common than primary Bone Cancer. Cancer cells typically travel through the bloodstream or lymphatic system, reaching bones and forming new tumors. The most frequent sources of metastasis to the bones include breast, lung, prostate, and kidney cancers. Metastatic bone disease often leads to weakened bones, causing pain, fractures, and other complications. Diagnostic tools like imaging studies and biopsies help identify the presence of metastases and determine the best course of treatment. Management involves a multidisciplinary approach, including systemic therapies such as chemotherapy, hormone therapy, or targeted therapies, along with localized interventions like radiation therapy or surgery to address specific bone lesions. While metastatic bone disease is challenging, advancements in cancer treatments and supportive care have improved outcomes and quality of life for individuals facing this condition. Early detection and a comprehensive treatment plan tailored to the patient's unique circumstances are crucial in managing metastatic bone disease effectively.
Title : Knotless suture repair for chronic lateral ankle instability: A systematic review & single- arm meta-analysis
Hussein Jaber, University of Cambridge, United Kingdom
Title : The UK profemur recall and implant cobaltism
Stephen S Tower, University of Alaska Anchorage, United States
Title : The tomographic phenotype and the genotype of wormain bones
Ali Al Kaissi, National Ilizarov Medical Research Center for Traumatology and Orthopaedics, Russian Federation
Title : Total Knee Arthroplasty (TKA) in hemophilic arthropathy: Modern outcomes and perioperative strategies
Jack Russek, Touro University California, United States
Title : Musculoskeletal and orthopedic implications of Gender-Affirming Hormone Therapy (GAHT): A PRISMA-Guided systematic narrative review
Jack Russek, Touro University California, United States