Metastatic Bone Disease, also known as secondary Bone Cancer, occurs when cancer cells from a primary tumor elsewhere in the body spread (metastasize) to the bones. This condition is more common than primary Bone Cancer. Cancer cells typically travel through the bloodstream or lymphatic system, reaching bones and forming new tumors. The most frequent sources of metastasis to the bones include breast, lung, prostate, and kidney cancers. Metastatic bone disease often leads to weakened bones, causing pain, fractures, and other complications. Diagnostic tools like imaging studies and biopsies help identify the presence of metastases and determine the best course of treatment. Management involves a multidisciplinary approach, including systemic therapies such as chemotherapy, hormone therapy, or targeted therapies, along with localized interventions like radiation therapy or surgery to address specific bone lesions. While metastatic bone disease is challenging, advancements in cancer treatments and supportive care have improved outcomes and quality of life for individuals facing this condition. Early detection and a comprehensive treatment plan tailored to the patient's unique circumstances are crucial in managing metastatic bone disease effectively.
Title : The etiological diagnosis of torticollis
Ali Al Kaissi, National Ilizarov Medical Research Center for Traumatology and Orthopaedics, Russian Federation, Russian Federation
Title : Selective denervation for persistent knee pain after total knee arthroplasty: Long-term outcomes
Shaomin Shi, Medical College of Wisconsin, United States
Title : AI-Driven infrared imaging and telerobotics in orthopedics: Enhancing diagnostics, surgical precision, and postoperative care
Marcos Brioschi, American Academy of Thermology, United States
Title : Efficacy and safety of negative pressure wound therapy in managing lower limb amputation: An updated systematic review and meta-analysis with individual patients data meta-analysis and GRADE assessment
Abdullah Elrefae, Northwick Park Hospital, United Kingdom
Title : Management of open fractures: Assessment of adherence to BOA guidelines regarding duration of antibiotics and timing of administration
Mohamed Farag, Nottingham University Hospitals NHS Trust, United Kingdom
Title : Postero Lateral Rotatory Instability (PLRI) of the elbow: Current concepts and the overlooked role of cubitus varus
Ahmad Quzli, North West NHS England, United Kingdom