Orthopaedic Oncology is a specialized branch of orthopedics dedicated to the diagnosis and treatment of primary and metastatic bone tumors and soft tissue sarcomas. Orthopaedic oncologists are highly trained surgeons who work in collaboration with a multidisciplinary team, including medical oncologists, radiation oncologists, and pathologists, to provide comprehensive care for patients with musculoskeletal cancers. Key aspects of orthopaedic oncology include the early detection of tumors, accurate staging, and the development of personalized treatment plans. Surgical interventions may involve limb-sparing procedures to preserve function and quality of life, or amputations in cases where it is medically necessary. Adjuvant therapies such as chemotherapy and radiation are often utilized to enhance treatment outcomes. Orthopaedic oncologists also play a crucial role in reconstructive surgery after tumor removal, utilizing techniques such as bone grafts or implants to restore form and function. Advances in imaging, pathology, and molecular diagnostics have significantly improved the precision of diagnosis and treatment planning in orthopaedic oncology. Given the complexity and rarity of musculoskeletal cancers, orthopaedic oncology emphasizes a patient-centered approach, providing not only effective treatment but also addressing the psychosocial and rehabilitation needs of individuals facing these challenging conditions. Ongoing research in orthopaedic oncology contributes to the development of innovative therapies and improves overall patient care.