Osteoarticular Tuberculosis is a rare form of tuberculosis that primarily affects the joints and bones. It occurs when the Mycobacterium tuberculosis bacteria infect the musculoskeletal system, leading to inflammation and destruction of joint and bone tissues. This form of tuberculosis can affect any joint, but it commonly involves the spine, hip, knee, and ankle. Symptoms include joint pain, swelling, stiffness, and sometimes the formation of abscesses. The diagnosis often involves clinical evaluation, imaging studies such as X-rays and MRI, and sometimes biopsy or aspiration of joint fluid. Treatment of osteoarticular tuberculosis typically includes a prolonged course of anti-tubercular medications, usually lasting several months. In some cases, surgical intervention may be necessary to address joint destruction, deformities, or complications such as abscess formation. Early detection and prompt treatment are crucial for preventing long-term joint damage and disability. Osteoarticular tuberculosis remains a significant challenge due to its insidious onset and potential for severe joint destruction if not managed appropriately.