Paget Disease Of Bone

Paget's Disease Of Bone, also known as osteitis deformans, is a chronic disorder characterized by abnormal bone remodeling, resulting in enlarged and weakened bones. It commonly affects the pelvis, spine, skull, and long bones. While the exact cause is unclear, genetic factors and viral infections may contribute. Symptoms include bone pain, deformities, and an increased risk of fractures. Diagnosis involves a combination of clinical evaluation, imaging studies like X-rays, and blood tests checking for elevated alkaline phosphatase levels. Treatment aims to alleviate symptoms and reduce complications. Bisphosphonates are commonly prescribed to regulate bone turnover, and in severe cases or when complications arise, surgical intervention may be necessary. Paget's disease can lead to secondary osteoarthritis and neurological complications, emphasizing the importance of early detection and appropriate management. Regular monitoring and a multidisciplinary approach involving orthopaedic specialists and endocrinologists are integral to the comprehensive care of individuals with Paget's disease of bone.